HL7Spy offers two mechanisms for accessing features without using a mouse:

Key Tips: Quick keyboard access to Ribbon pages, page groups, and buttons is provided through Key Tips. Pressing and releasing the ALT or F10 key displays shortcuts above the toolbar buttons. Pressing the key associated with the shortcut executes it or displays a list of sub-item shortcuts that can be activated. For instance, Alt-H, MA toggles masking on/off.
Keyboard Shortcuts: An alternative mechanism to Key Tips for accessing a subset of HL7Spy's functionality without a mouse. A table of keyboard shortcuts can be found below.

Tool Navigation

Ctrl+Tab	Switch Focus between the Editor and Segment Editor
Ctrl+P	Open message property window for the selected message
Ctrl+E	Show Segment Editor view
Ctrl+Shfit+M	Merge Message tabs
Ctrl+W	Show the Watch List view
Ctrl+Shift+S	Sort Message tab
Ctrl+Shift+W	Generate watch list report
Ctrl+Shift+R	Generate clean up message collection tool
F1	Show HL7 Standard view

Ctrl+Left	Move to previous non-null field
Ctrl+Right	Move to next non-null field
Alt+Right	Go to next message
Alt+Left	Go to the previous message
Ctrl+Home	Go to the first message
Ctrl+End	Go to the last message
Ctrl+(0-9)	Move to a specific field number. E.G. Ctrl+19 moves to field 19 in the current segment.
Ctrl+G	Go to a specific message index.

Ctrl+Up	Go to the previous segment
Ctrl+Down	Go to the next segment
Right	Go to next field
Left	Go to the previous field
Ctrl+T	Toggle “Show Empty Components” and “Show Empty Fields”

Ctrl+F	Show Find Message dialog
F3	Search Next
Ctrl+Shift+F	Quick Find Message text
Ctrl+Shift+Down	Quick Find Next
Ctrl+Shift+Up	Quick Find Previous
Ctrl+Shift+H	Highlight specific field within the message

Ctrl+N	Open new message tab
Ctrl+O	Open File
Ctrl+X	Close File (clicking on the message tab with the middle mouse button will do the same)
Ctrl+Shift+X	Close all files
Ctrl+S	Save File
Ctrl+H	Open file with the hex editor

Ctrl+Shift+W	Add current selection to Watch List
Ctrl+Space	Show statistics for the selected component
Ctrl+Shift+Space	Show statistics for the selected field
Ctrl+Alt+Space	Show statistics for selected sub-component
Ctrl+Shift+Space	Show statistics for the selected field
Ctrl+Shift+A	Show advanced statistics for the selected area
Ctrl+Mouse	Hovering over a field with the Ctrl key pressed will display a tooltip with the field description